A downward trend of new cases has been reported at Médecins Sans Frontières/Doctors Without Borders (MSF) Ebola management centres across Guinea, Liberia and Sierra Leone, with just over 50 patients currently in eight centres. While this is a promising development, the medical humanitarian organization cautions that loss of vigilance now would jeopardize the progress made in stemming the epidemic.

“This decline is an opportunity to focus efforts on addressing the serious weaknesses that remain in the response,” says Brice de la Vingne, MSF’s director of operations.  “We are on the right track, but reaching zero cases will be difficult unless significant improvements are made in alerting new cases and tracing those who have been in contact with them.”

The World Health Organization reported last week that only about half of new cases in both Guinea and Liberia are from known Ebola contacts, while in Sierra Leone there is no data available. “A single new case is enough to reignite an outbreak,” continues de la Vingne. “Until everyone who has come into contact with Ebola has been identified, we cannot rest easy.”

There is almost no information sharing for tracing Ebola contacts between the three most-affected countries. “With people moving frequently across borders, it is essential that surveillance teams based in each country collaborate immediately so that new cases are not imported into areas considered Ebola-free,” says de la Vingne. “This is a regional problem, not a country-specific one, but it is not being dealt with as such.”

 

Sierra Leone: cases decreasing but hotspots persist

In the past two weeks, reported cases of Ebola across Sierra Leone have declined to the lowest since August. The situation appears to be improving faster in remote, rural areas such as Kailahun district, a former Ebola hotspot where MSF began working in late June 2014. The comprehensive response — with an early emphasis on health promotion, contact tracing and monitoring, and a small number of organizations working together — contributed to bringing the disease under control in this district, which has seen no new cases since December 12, 2014.

Despite these encouraging signs, some hotspots persist, notably the capital Freetown, the Western Rural Area and Port Loko district. MSF’s busiest Ebola management centre is currently the Prince of Wales centre, in Freetown, with 30 patients as of January 24.

 

• Trial of possible Ebola drug begins at MSF treatment centre

 

Stopping transmission is particularly difficult in the overcrowded slum areas of the capital, Freetown. Elsewhere, tracing contacts of Ebola patients is still not being carried out systematically, while many contacts are being forcibly quarantined in their homes, at times experiencing shortages of food or water. These quarantine measures can discourage families from seeking early treatment for their sick relatives for fear of being locked in their homes.

“An added struggle is the paralysis of the public health system,” says Karline Kleijer, MSF’s emergency coordinator. “One in ten of the country’s health workers have died of Ebola, the medical facilities are in disarray, and people with non-Ebola illnesses struggle to get the treatment they need.”

Last week, MSF teams provided 1.8 million anti-malarials in Freetown, the largest ever distribution in an Ebola outbreak.

 

Guinea: stigma and fear still problematic

Guinea has also seen a steep decrease in new cases; however 14 out of the 33 prefectures in the country are still considered as “active.”  New cases appear to be originating from areas of the country that were previously regarded as calm, such as Boké, Dabola and Siguiri.

Together with surveillance, health promotion and social mobilization are inadequate and failing to make significant progress today in Guinea. “Health workers and survivors are stigmatized, people are still reluctant to seek care, and Ebola treatment centres are often regarded with suspicion and fear,” says Henry Gray, MSF’s emergency coordinator for Guinea.

MSF is currently running two Ebola management centres in Guinea, as well as conducting surveillance, social mobilization and trainings in infection control. A rapid response team is in place to address needs as they arise.

 

Liberia: safe reopening of the public health system an urgent priority

Liberia has seen the sharpest decline in Ebola cases, with only five confirmed cases currently reported in the country. On January 17, for the first time since it opened, there were no Ebola patients in MSF’s ELWA 3 Ebola management centre in Monrovia; today there are now just two.

Liberia’s already weak public-health system has been seriously damaged by the epidemic, with many hospitals shut down. Though some are beginning to reopen, infection control is crucial to mitigate the risk of Ebola and restore public confidence in the health system. In response, MSF supports 13 health centres with infection prevention and control, and is opening a 100-bed pediatric hospital in Monrovia.

An MSF rapid-response team is also running mobile clinics, training local health staff in triage and infection control, and filling gaps in primary healthcare. Between October and December 2014, MSF distributed anti-malarials to nearly 600,000 people in Monrovia to reduce the burden of malaria infections.

 

MSF and the ongoing Ebola response

MSF is currently running eight Ebola Management Centres across Sierra Leone, Guinea and Liberia. Rapid response teams are in place ready to care for emerging cases, while other MSF teams are also conducting surveillance, social mobilization and trainings in infection control in health centres. Since the outbreak began, the organization has cared for almost 5,000 patients, approximately 25 per cent of all declared cases.  Additionally, MSF is currently involved in two clinical trials of experimental treatments in conjunction with Oxford University in Liberia and INSERM in Guinea. More than 4,000 MSF staff are working across the three countries.